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Eritoran, a Gram-negative bacterial endotoxin blocker, fails Phase 3 clinical trial

by admin | Mar 26, 2013 | Uncategorized

Eritoran, a promising first-in-class agent for combating Gram-negative sepsis, failed its Phase 3 clinical trial, according to the results of the ACCESS trial published in the March 20th issue of JAMA. Eritoran is synthetic lipid A antagonist that blocks...

Use of procalcitonin guidance for early antibiotic discontinuation in sepsis

by admin | Mar 20, 2013 | Uncategorized

Early antibiotic administration is a critical step in appropriate sepsis care. However, overuse and misuse of antibiotics, including the unnecessarily prolonged use of antibiotics, can have adverse effects and lead to increased microbial resistance. A Comparative...
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